SII head Adar Poonawalla, 39, is planning to begin production of a SARS-CoV-2 vaccine now. By autumn, he hopes to have produced 40 million doses, at which time it will become clear if it is granted approval – or not.
If it is approved, Poonawalla intends to make at least half of the doses available to India, with the rest going to countries that don’t have their own vaccine. If approval is not forthcoming, it will all be discarded.
Poonawalla’s company joined the project at its own risk. In the worst-case scenario, he might lose a few million euros of his multi-billion-euro nest egg. But should everything go well, he’ll be a hero by the end of the year – and have the reputation for being a visionary businessman.
The remoteness of the risk is always the hardest part to get our heads around. Our past moments of calm or our current nightmare, like the last coin flip or turn of the roulette wheel, tell us nothing about when the next one might arrive. One in 500 years isn’t a prophesy, just a probability. If anything, as Wolfe pointed out when I first met him over a decade ago, global warming, urbanization, and destruction of species habitats are only accelerating the speed at which the next pandemic may arrive.
In The Lonely City: Adventures in the Art of Being Alone, Olivia Laing tells the stories of a number of artists who led isolated lives and found meaning in their work even if their relationships couldn’t fulfill them. While she focuses specifically on visual artists in New York over the last seventy years, their methods of using their loneliness and transmitting it into their art carry wide resonance. These particular artists tapped into sentiments many of us will experience at least once in our lives. They found beauty in loneliness and showed it to be something worth considering, not just something to run from.
This point cannot be overstated: The pandemic patchwork exists because the U.S. is a patchwork to its core. New outbreaks will continue to flare and fester unless the country makes a serious effort to protect its most vulnerable citizens, recognizing that their risk is the result of societal failures, not personal ones. “People say you can’t fix the U.S. health system overnight, but if we’re not fixing these underlying problems, we won’t get out of this,” says Sheila Davis of Partners in Health. “We’ll just keep getting pop-ups.”
But he has always played with other people’s money and other people’s lives. “The president was probably in a position to make riskier decisions in life because he was fabulously rich from birth,” says Murphy. “But it’s also true he has had a reputation for risk not backed up by reality. His name is on properties he doesn’t own. We think of him as taking risk in professional life, but a lot of what he does is lend his name to buildings with risks taken by others. He’s built an image as a risk taker, but it’s not clear how much risk he’s taken.”
The results of his initial trial have yet to be replicated. “I think what he secretly hopes is that no one will ever be able to show anything,” Molina told me. “That all the trials conducted on hydroxychloroquine will not be able to even reach a conclusion of no efficacy.” In recent weeks, Raoult has in fact tempered his claims about the virtues of his treatment regimen. The published, peer-reviewed version of the final study noted that another two patients had died, bringing the total to 10. Where the earlier version called the drugs “safe and efficient,” they were now described merely as “safe.”
He has shown flickers of what appears to be doubt. In one interview, Raoult quoted Camus, from the fatalistic coda of “The Stranger,” hoping that “on the day of my execution there should be a huge crowd of spectators, and that they should greet me with howls of hatred.”
In the United States, according to the National Institutes of Health, between two and four of every 100,000 children are born with Batten disease. They can get it if both their parents are genetic carriers. There are 14 subtypes of the disease, each affecting a different gene, involving a different deficiency, and decreeing a different life span. Conner was diagnosed with subtype CLN2, distinguished by the absence of TPP1. Symptoms initially appear around the age of two; a speech delay is often the first noticeable sign of disease. After that come seizures, language regression, motor dysfunction, and blindness. Patients die between the ages of eight and twelve.
According to psychologist, psychotherapist and hypnotherapist Dr Jonathan Pointer, the appeal in returning to treasured TV, films, music, books, video games, sporting moments, and even food, lies in the connection between emotion and memory. “Emotions and memories are linked; emotions reactivate memories, and memories reactivate emotions. So nostalgic reminiscence, when we create an emotional response through reminiscing on past events, is an easy way to re-experience an emotion attached to a particular memory. This can be aided by retrieval cues, such as smells, sights, sounds, from our past,” he says.
Which searches are trending?
There are things that are concerning for society like the spike in searches for “loneliness,” people searching for “having trouble sleeping,” “depression.” All of those things are concerning to me, and I worry for people that don’t have people with them or are feeling it. Then the other misinformation thing is really interesting, because normally around any political thing, you always see spikes and searches where people are trying to find out if a misinfo story is true.
In this pandemic, the mask reveals far more than it hides. It exposes the world’s political and economic relations for what they are: vectors of self-interest that ordinarily lie obscured under glib talk of globalisation and openness. For the demagogues who govern so much of the world, the pandemic has provided an unimpeachable excuse to fulfil their dearest wishes: to nail national borders shut, to tar every outsider as suspicious, and to act as if their own countries must be preserved above all others.